Anthony Altieri

The paper investigates the role of Pi16+ fibroblasts in regulating macrophage homeostasis and skin architecture by analyzing the effects of Csf1 deletion in these cells.

This study shows LL-37 enhances pro-inflammatory oxylipins and chemokines via COX-2 and P2X7 receptor, while citrullinated LL-37 reduces these effects.

This study shows Bigh3 is essential for lung fibrosis by demonstrating its role in fibroblast-macrophage interactions and collagen expression.

This study shows LL-37 and its citrullinated form suppress IL-17A/F-induced LCN-2 production in bronchial epithelial cells, reducing neutrophil migration and airway inflammation.

This study identifies Dpt+ fibroblasts as essential for maintaining a Csf1-dependent macrophage niche in skin, with implications for wound healing and scleroderma.