Author

E. A. DePasquale

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:deep learning· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

A. A. Lane· 1 shared A. K. Shalek· 1 shared A. L. Peters· 1 shared C. Couturier· 1 shared D. A. Hildeman· 1 shared D. Ssozi· 1 shared E. S. Woodle· 1 shared G. Begum· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. A. Lane

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2 papers

Recent·Most cited

Defining the T cell transcriptional landscape in pediatric liver transplant rejection at single cell resolution

A. L. Peters, E. A. DePasquale, G. Begum, K. M. Roskin, E. S. Woodle, D. A. Hildeman

This study defines the transcriptional landscape of CD8+ T cells in pediatric liver transplant rejection using single-cell sequencing and identifies persistent CD8+ clones associated with graft failure.

bioRxiv · Feb 26, 2024Immunology

Single-cell Multiomics Reveals Clonal T-cell Expansions and Exhaustion in Blastic Plasmacytoid Dendritic Cell Neoplasm

E. A. DePasquale, D. Ssozi, M. Ainciburu, J. Good, J. Noel, M. Villanueva, C. Couturier, A. K. Shalek, S. F. Aranki, H. R. Mallidi, G. K. Griffin, A. A. Lane, P. van Galen

This study uses single-cell multiomics to analyze T-cell responses in BPDCN, finding upregulated IFNA and downregulated TNFA pathways, along with T-cell exhaustion and clonotype expansion.

bioRxiv · Dec 1, 2021Immunology