Author

D. A. Hildeman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 4 Assay:scRNA-seq· 4 Research Focus:cell-cell communication· 3 Organism:human· 3 Approach:deep learning· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2

Frequent Co-Authors

E. S. Woodle· 3 shared A. Arazi· 1 shared A. Barski· 1 shared A. Chicoine· 1 shared A. Davidson· 1 shared A. Godarova· 1 shared A. H. Jonsson· 1 shared A. Katko· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

E. S. Woodle

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Defining the T cell transcriptional landscape in pediatric liver transplant rejection at single cell resolution

A. L. Peters, E. A. DePasquale, G. Begum, K. M. Roskin, E. S. Woodle, D. A. Hildeman

This study defines the transcriptional landscape of CD8+ T cells in pediatric liver transplant rejection using single-cell sequencing and identifies persistent CD8+ clones associated with graft failure.

bioRxiv · Feb 26, 2024Immunology

An atlas of gene regulatory networks for memory CD4+ T cells in youth and old age

J. A. Wayman, A. Thomas, A. T. Bejjani, A. Katko, M. Almanan, A. Godarova, S. Korinfskaya, T. A. Cazares, M. Yukawa, L. C. Kottyan, A. Barski, C. A. Chougnet, D. A. Hildeman, E. R. Miraldi

The paper constructs an atlas of gene regulatory networks for memory CD4+ T cells in young and old mice, revealing age-related changes in transcription factor control and cell-cell communication.

bioRxiv · Mar 7, 2023 · PreprintImmunology

Single cell transcriptomic analysis of renal allograft rejection reveals novel insights into intragraft TCR clonality

T. Shi, A. R. Burg, J. T. Caldwell, K. Roskin, C. M. C. Rojas, P. C. Chukwuma, G. I. Gray, S. G. Foote, J. Alonso, C. M. Cuda, D. A. Allman, J. S. Rush, C. H. Regnier, G. Wieczorek, R. R. Alloway, , D. A. Hildeman

The paper uses single-cell RNA sequencing and TCR sequencing to analyze renal allograft rejection, finding CD8+ T cell clonal expansion linked to rejection, independent of immunosuppression type.

bioRxiv · Feb 8, 2023Immunology

The immune cell landscape in kidneys of lupus nephritis patients

A. Arazi, D. A. Rao, C. C. Berthier, A. Davidson, Y. Liu, P. J. Hoover, A. Chicoine, T. M. Eisenhaure, A. H. Jonsson, S. Li, D. J. Lieb, E. P. Browne, A. Noma, D. Sutherby, S. Steelman, , B. Diamond

This study uses single-cell RNA-seq to analyze immune cell subsets in lupus nephritis kidneys, identifying pro-inflammatory and resolving responses and potential therapeutic targets.

bioRxiv · Jul 7, 2018Immunology