Author

G. K. Griffin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

A. A. Lane· 2 shared A. K. Shalek· 1 shared A. Louissaint· 1 shared C. Couturier· 1 shared D. M. Weinstock· 1 shared D. Ssozi· 1 shared E. A. DePasquale· 1 shared E. A. Morgan· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

A. A. Lane

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Single-cell Multiomics Reveals Clonal T-cell Expansions and Exhaustion in Blastic Plasmacytoid Dendritic Cell Neoplasm

E. A. DePasquale, D. Ssozi, M. Ainciburu, J. Good, J. Noel, M. Villanueva, C. Couturier, A. K. Shalek, S. F. Aranki, H. R. Mallidi, G. K. Griffin, A. A. Lane, P. van Galen

This study uses single-cell multiomics to analyze T-cell responses in BPDCN, finding upregulated IFNA and downregulated TNFA pathways, along with T-cell exhaustion and clonotype expansion.

bioRxiv · Dec 1, 2021Immunology

Sex-biased ZRSR2 mutations in myeloid malignancies impair plasmacytoid dendritic cell activation and apoptosis

K. Togami, S. S. Chung, V. Madan, L. Cabal-Hierro, J. Taylor, S. S. Kim, G. K. Griffin, M. Ghandi, J. Li, Y. Y. Li, F. Angelot-Delettre, S. Biichle, M. Seiler, S. Buonamici, S. B. Lovitch, , A. A. Lane

The paper identifies sex-biased ZRSR2 mutations in BPDCN that impair pDC activation and apoptosis, linking X chromosome mutations to male-predominant leukemia.

bioRxiv · Oct 29, 2020Cancer Biology