Author

E. S. Woodle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:human· 4 Research Focus:differential expression· 3 Approach:experimental assay· 3 Assay:scRNA-seq· 3 Research Focus:cell-cell communication· 2 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

D. A. Hildeman· 3 shared A. Arazi· 2 shared C. C. Berthier· 2 shared C. Putterman· 2 shared D. L. Kamen· 2 shared D. Wofsy· 2 shared F. Payan-Schober· 2 shared K. C. Kalunian· 2 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

D. A. Hildeman

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4 papers

Recent·Most cited

Defining the T cell transcriptional landscape in pediatric liver transplant rejection at single cell resolution

A. L. Peters, E. A. DePasquale, G. Begum, K. M. Roskin, E. S. Woodle, D. A. Hildeman

This study defines the transcriptional landscape of CD8+ T cells in pediatric liver transplant rejection using single-cell sequencing and identifies persistent CD8+ clones associated with graft failure.

bioRxiv · Feb 26, 2024Immunology

Blood immunophenotyping identifies distinct kidney histopathology and outcomes in patients with lupus nephritis

A. Horisberger, A. Griffith, J. Keegan, A. Arazi, J. Pulford, E. Murzin, K. Howard, B. Hancock, A. Fava, T. Sasaki, T. Ghosh, J. Inamo, R. Beuschel, Y. Cao, K. Preisinger, , Accelerating Medicines Pa

The paper identifies three immunologically distinct groups in lupus nephritis patients based on blood immunophenotyping, correlating with histopathology, treatment response, and renal outcomes.

bioRxiv · Jan 14, 2024Immunology

Single cell transcriptomic analysis of renal allograft rejection reveals novel insights into intragraft TCR clonality

T. Shi, A. R. Burg, J. T. Caldwell, K. Roskin, C. M. C. Rojas, P. C. Chukwuma, G. I. Gray, S. G. Foote, J. Alonso, C. M. Cuda, D. A. Allman, J. S. Rush, C. H. Regnier, G. Wieczorek, R. R. Alloway, , D. A. Hildeman

The paper uses single-cell RNA sequencing and TCR sequencing to analyze renal allograft rejection, finding CD8+ T cell clonal expansion linked to rejection, independent of immunosuppression type.

bioRxiv · Feb 8, 2023Immunology

The immune cell landscape in kidneys of lupus nephritis patients

A. Arazi, D. A. Rao, C. C. Berthier, A. Davidson, Y. Liu, P. J. Hoover, A. Chicoine, T. M. Eisenhaure, A. H. Jonsson, S. Li, D. J. Lieb, E. P. Browne, A. Noma, D. Sutherby, S. Steelman, , B. Diamond

This study uses single-cell RNA-seq to analyze immune cell subsets in lupus nephritis kidneys, identifying pro-inflammatory and resolving responses and potential therapeutic targets.

bioRxiv · Jul 7, 2018Immunology