Author

M. Ainciburu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Immunology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 4 Organism:human· 4 Approach:deep learning· 3 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Assay:scRNA-seq· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. Molero· 2 shared F. Prosper· 2 shared G. Serrano· 2 shared J. Montoro· 2 shared P. van Galen· 2 shared T. Jimenez· 2 shared A. A. Lane· 1 shared A. Alfonso Pierola· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

A. Molero

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Single cell profiling of del(5q) MDS unveils its transcriptional landscape and the impact of lenalidomide

G. Serrano, N. Berastegui Zufiaurre, A. Diaz Mazkiaran, P. Garcia Olloqui, S. Huerga Dominguez, A. Alfonso Pierola, A. Ullate Agote, B. Ariceta Ganuza, M. Ainciburu, A. Vilas Zornoza, P. San Martin Uriz, P. Aguirre Ruiz, J. M. Lamo de Espinosa, P. Acha, O. Calvete, , M. Hernaez Arrazola

This study uses scRNA-seq to analyze del(5q) MDS patients, revealing shared and unique transcriptional alterations and lenalidomide's impact on disease and treatment response.

bioRxiv · Oct 19, 2023 · PreprintCancer Biology

WAT3R: Recovery of T-Cell Receptor Variable Regions From 3' Single-Cell RNA-Sequencing

M. Ainciburu, D. M. Morgan, E. A. K. DePasquale, J. C. Love, F. Prosper, P. van Galen

WAT3R recovers T-cell receptor variable regions from 3' scRNA-seq data, enabling T-cell clonotype reconstruction and analysis of TCR sequences in single cells.

bioRxiv · Jan 26, 2022Immunology

Single-cell Multiomics Reveals Clonal T-cell Expansions and Exhaustion in Blastic Plasmacytoid Dendritic Cell Neoplasm

E. A. DePasquale, D. Ssozi, M. Ainciburu, J. Good, J. Noel, M. Villanueva, C. Couturier, A. K. Shalek, S. F. Aranki, H. R. Mallidi, G. K. Griffin, A. A. Lane, P. van Galen

This study uses single-cell multiomics to analyze T-cell responses in BPDCN, finding upregulated IFNA and downregulated TNFA pathways, along with T-cell exhaustion and clonotype expansion.

bioRxiv · Dec 1, 2021Immunology

Transcriptional regulation of HSCs in Aging and MDS reveals DDIT3 as a Potential Driver of Dyserythropoiesis

N. Berastegui, M. Ainciburu, J. P. Romero, A. Alfonso-Pierola, C. Philippe, A. Vilas-Zornoza, P. San Martin, R. Ordonez, D. O. Alignani, S. Sarvide, L. Castro, J. M. Lamo-Espinosa, M. San-Julian, T. Jimenez, F. Lopez Cardenas, , F. Prosper

This study identifies DDIT3 as a driver of dyserythropoiesis in MDS by showing its upregulation in HSCs and its ability to disrupt erythropoiesis when overexpressed.

bioRxiv · Sep 8, 2021 · PreprintCancer Biology