Author

E. A. Morales

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Assay:proteomics· 3 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

M. J. Tyska· 2 shared A. Wang· 1 shared C. Arnaiz· 1 shared D. Atanackovic· 1 shared E. Rosati· 1 shared E. S. Krystofiak· 1 shared E. Vander Mause· 1 shared F. Iglesias· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

M. J. Tyska

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Restricting CAR T Cell Trafficking Expands Targetable Antigen Space

E. A. Morales, K. A. Dietze, J. M. Baker, A. Wang, S. V. Avila, F. Iglesias, S. V. Radhakrishnan, E. Vander Mause, M. L. Olson, W. Sun, E. Rosati, S. L. Chidester, T. Iraguha, X. Fan, D. Atanackovic, T. Luetkens

The paper shows that modifying integrin-mediated adhesion in CAR T cells prevents CNS targeting while maintaining anti-tumor activity against Ewing sarcoma.

bioRxiv · Feb 8, 2024 · PreprintBioengineering

Mitotic spindle positioning protein (MISP) is an actin bundler that senses ADP-actin and binds near the pointed ends of filaments

E. A. Morales, M. J. Tyska

This study shows MISP binds preferentially to ADP-actin filaments near their pointed ends, forming parallel bundles and modulating microvilli structure.

bioRxiv · May 5, 2023 · PreprintCell Biology

Mitotic Spindle Positioning (MISP) is an actin bundler that selectively stabilizes the rootlets of epithelial microvilli

E. A. Morales, C. Arnaiz, E. S. Krystofiak, M. Zanic, M. J. Tyska

The paper identifies MISP as an actin bundler that stabilizes microvillus rootlets and reveals its interaction with ezrin to maintain bundle structure.

bioRxiv · Aug 2, 2021 · PreprintCell Biology