Author

S. V. Avila

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

F. Iglesias· 2 shared M. L. Olson· 2 shared S. V. Radhakrishnan· 2 shared T. Luetkens· 2 shared A. Wang· 1 shared D. Atanackovic· 1 shared E. A. Morales· 1 shared E. Morales· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersBioengineering

F. Iglesias

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Restricting CAR T Cell Trafficking Expands Targetable Antigen Space

E. A. Morales, K. A. Dietze, J. M. Baker, A. Wang, S. V. Avila, F. Iglesias, S. V. Radhakrishnan, E. Vander Mause, M. L. Olson, W. Sun, E. Rosati, S. L. Chidester, T. Iraguha, X. Fan, D. Atanackovic, T. Luetkens

The paper shows that modifying integrin-mediated adhesion in CAR T cells prevents CNS targeting while maintaining anti-tumor activity against Ewing sarcoma.

bioRxiv · Feb 8, 2024 · PreprintBioengineering

Targeted delivery of interferon-gamma by synNotch T cells sensitizes neuroblastoma cells to T cell-mediated killing

F. Iglesias, S. Weston, S. V. Avila, H. Zhou, S. Yousef, M. Fluchel, E. Morales, M. L. Olson, S. V. Radhakrishnan, T. Luetkens

This study develops synNotch T cells that deliver IFN-gamma to neuroblastoma cells, restoring HLA expression and enhancing T cell-mediated killing without increasing immune checkpoints or systemic IFN-gamma.

bioRxiv · Jun 21, 2022 · PreprintBioengineering