Author

E. A. Otto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Pathology· 1 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Research Focus:batch correction / integration· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

R. Menon· 2 shared A. Al-Suraimi· 1 shared A. C. Telang· 1 shared A. Schroeder· 1 shared A. Soofi· 1 shared B. B. Lake· 1 shared B. Rovin· 1 shared B. Steck· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPathology

R. Menon

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Pax Protein Depletion in Proximal Tubules Triggers Conserved Mechanisms of Resistance to Acute Ischemic Kidney Injury and Prevents Transition to Chronic Kidney Disease

J. A. Beamish, A. C. Telang, M. C. McElliott, A. Al-Suraimi, M. Chowdhury, J. T. Ference-Salo, E. A. Otto, R. Menon, A. Soofi, J. M. Weinberg, S. R. Patel, G. R. Dressler

This study shows that deleting Pax2 and Pax8 in proximal tubules reduces acute kidney injury severity and prevents chronic disease by inducing protective gene expression similar to preconditioning.

bioRxiv · Oct 3, 2023 · PreprintPathology

A Multimodal and Integrated Approach to Interrogate Human Kidney Biopsies with Rigor and Reproducibility: The Kidney Precision Medicine Project

T. M. El-Achkar, M. T. Eadon, R. Menon, B. B. Lake, T. K. Sigdel, T. Alexandrov, S. Parikh, G. Zhang, D. Dobi, K. W. Dunn, E. A. Otto, C. R. Anderton, J. M. Carson, J. Luo, C. Park, , For the Kidney Precision Medicine Project

The paper describes a pipeline for generating 3D molecular atlases of human kidney biopsies using multi-OMICS and imaging technologies, emphasizing quality control and reproducibility across institutions.

bioRxiv · Aug 23, 2020 · PreprintScientific Communication & Education