Author

E. A. Rakha

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:clinical cohort / trial· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. R. Green· 3 shared A. C. Vargas· 1 shared A. Ditsiou· 1 shared A. E. McCart Reed· 1 shared A. Hasson· 1 shared A. J. Dalley· 1 shared A. Murugasu· 1 shared A. Raghavendra· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCancer Biology

A. R. Green

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Author profile →

3 papers

Recent·Most cited

Utility of stromal lymphocytes in diagnosis and predicting upgrade of B3 breast lesions from core biopsies

T. Kader, S. Hendry, E. Provenzano, M. W. Jayawardana, J.-M. Pang, K. Elder, D. J. Byrne, L. Tjoeka, H. M. Frazer, E. House, S. Jayasinghe, H. Keane, A. Murugasu, N. Rajan, I. M. Miligy, , K. L. Gorringe

This study identifies stromal lymphocytes as a biomarker to predict upgrade of B3 breast lesions from core biopsies, with high specificity.

bioRxiv · Sep 2, 2022 · PreprintCancer Biology

Epigenome erosion drives neural crest-like phenotypic mimicry in triple-negative breast cancer and other SOX10+ malignancies

J. M. Saunus, X. M. De Luca, K. Northwood, A. Raghavendra, A. Hasson, A. E. McCart Reed, M. Lim, S. Lal, A. C. Vargas, J. R. Kutasovic, A. J. Dalley, M. Miranda, E. Kalaw, P. Kalita-de Croft, I. Gresshoff, , S. R. Lakhani

The paper identifies SOX10 expression in TNBC and other SOX10+ malignancies, linking it to epigenome erosion and neural crest-like phenotypic mimicry through promoter hypomethylation.

bioRxiv · Mar 30, 2021 · PreprintCancer Biology

Global kinome silencing combined with 3D invasion screening of the tumor microenvironment identifies fibroblast-expressed PIK3Cδ involvement in triple-negative breast cancer progression

T. Gagliano, K. Shah, S. Gargani, L. Lao, M. Alsaleem, J. Chen, V. Ntafis, P. Huang, A. Ditsiou, V. Vella, K. Yadav, K. Bienkowska, G. Bresciani, K. Kang, L. Li, , G. Giamas

The paper identifies fibroblast-expressed PIK3Cδ as a key driver of triple-negative breast cancer progression through paracrine signaling and shows its prognostic significance.

bioRxiv · Nov 2, 2019 · PreprintCancer Biology