Author

E. Bowie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

K. V. Anderson· 1 shared R. Norris· 1 shared S. C. Goetz· 1 shared S. Goetz· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 3 mutual co-author links

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1 shared paperCell Biology

K. V. Anderson

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2 papers

Recent·Most cited

TTBK2 and primary cilia are essential for the connectivity and survival of cerebellar Purkinje neurons

E. Bowie, S. C. Goetz

This study shows that TTBK2 and primary cilia are essential for cerebellar Purkinje neuron connectivity and survival, with loss of cilia leading to neurodegeneration similar to SCA11.

bioRxiv · Jul 2, 2019Cell Biology

Spinocerebellar ataxia type 11-associated alleles of Ttbk2 dominantly interfere with ciliogenesis and cilium stability.

E. Bowie, R. Norris, K. V. Anderson, S. Goetz

This study shows that SCA11-associated TTBK2 mutations act as dominant negative alleles that disrupt ciliogenesis and cilia-dependent signaling, contributing to neurodegeneration.

bioRxiv · Nov 6, 2018Cell Biology