R. Norris

The Implant-Induced Foreign Body Response is Limited by CD13-Dependent Regulation of Ubiquitination of Fusogenic Proteins

This study shows CD13 regulates macrophage fusion by controlling ubiquitination of fusogenic proteins, limiting foreign body response fibrosis and suggesting CD13 as a therapeutic target.

Cardiac Effects of a Novel pH-Insensitive Sodium-Calcium Exchanger Mouse

This study creates a pH-insensitive NCX1 mouse and finds it has reduced growth, accelerated cardiac repolarization, and is resistant to ischemia/reperfusion injury.

Homophilic interaction of E-Cadherin prevents cell-cell fusion between developing germline and surrounding epithelia in Drosophila ovary

This study shows that E-Cadherin homophilic interaction prevents cell-cell fusion between germline and follicle cells in Drosophila ovary, maintaining tissue boundaries and cyst individualization.

Gap junction internalization and processing in vivo: a 3D immuno-electron microscopy study

The paper studies connexosome formation and processing in ovarian follicles using 3D immuno-electron microscopy, showing fission, membrane separation, and organelle transfer between cells.

Spinocerebellar ataxia type 11-associated alleles of Ttbk2 dominantly interfere with ciliogenesis and cilium stability.

This study shows that SCA11-associated TTBK2 mutations act as dominant negative alleles that disrupt ciliogenesis and cilia-dependent signaling, contributing to neurodegeneration.