Centrioles control the capacity, but not the specificity, of cytotoxic T cell killing
F. Tamzalit, D. Tran, W. Jin, V. Boyko, H. Bazzi, A. Kepecs, L. C. Kam, K. V. Anderson, M. Huse
This study shows that centrioles affect the capacity but not the specificity of cytotoxic T cell killing by impacting granule biogenesis and actin remodeling, not granule polarization.
bioRxiv · Jul 22, 2019Immunology