Author

E. Brownhill

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. Gimelbrant· 1 shared B. Bhattacharya· 1 shared B. N. Kholodenko· 1 shared H. A. Chen· 1 shared I. Kramnik· 1 shared K. Seidel· 1 shared L. Kobzik· 1 shared N. Crossland· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

A. Gimelbrant

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1 paper

Recent·Most cited

Maladaptive oxidative stress cascade drives type I interferon hyperactivity in TNF activated macrophages promoting necrosis in murine tuberculosis granulomas

E. Brownhill, S. M. Yabaji, V. Zhernovkov, O. S. Rukhlenko, K. Seidel, B. Bhattacharya, S. Chatterjee, H. A. Chen, N. Crossland, W. Bishai, B. N. Kholodenko, A. Gimelbrant, L. Kobzik, I. Kramnik

This study identifies a maladaptive oxidative stress cascade in TNF-activated macrophages that drives IFN-I hyperactivity and necrosis in murine tuberculosis granulomas, with potential therapeutic targets identified.

bioRxiv · Dec 14, 2020 · PreprintImmunology