The neonatal microenvironment programs conventional and intestinal Tbet+ γδT17 cells through the transcription factor STAT5
D. Kadekar, R. Agerholm, J. Rizk, H. Neubauer, T. Suske, B. Maurer, M. T. Vinals, E. Comelli, A. Taibi, R. Moriggl, V. Bekiaris
This study shows STAT5 is critical for neonatal expansion of γδT17 cells, which acquire tissue-specific traits necessary for immunity and autoimmunity.
bioRxiv · Jun 3, 2019Immunology