UNC-45A Weakens and Breaks MT Lattice Independent of its Effect on Non-Muscle Myosin II
M. Bazzaro, J. Habicht, A. Mooneyham, A. Hoshino, M. Shetty, X. Zhang, E. Emmings, Q. Yang, C. Coombes, M. K. Gardner
This study shows UNC-45A weakens and breaks microtubule lattices independently of its effect on non-muscle myosin II, with implications for disease treatment.
bioRxiv · Jun 20, 2020Cell Biology