A mitochondrial iron-sensing pathway regulated by DELE1
Y. Sekine, R. Houston, E. Fessler, L. T. Jae, D. P. Narendra, S. Sekine
This study identifies DELE1 as a mitochondrial protein whose import and stability are regulated by iron availability, linking mitochondrial function to the heme-regulated kinase HRI-mediated stress response.
bioRxiv · Apr 14, 2022 · PreprintCell Biology