Author

D. P. Narendra

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

S. Sekine· 3 shared J. Poulton· 2 shared R. Houston· 2 shared X. Huang· 2 shared Y. Sekine· 2 shared A. F. Powers· 1 shared B. B. Chen· 1 shared B. P. Wu· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersCell Biology

S. Sekine

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Author profile →

4 papers

Recent·Most cited

A mitochondrial iron-sensing pathway regulated by DELE1

Y. Sekine, R. Houston, E. Fessler, L. T. Jae, D. P. Narendra, S. Sekine

This study identifies DELE1 as a mitochondrial protein whose import and stability are regulated by iron availability, linking mitochondrial function to the heme-regulated kinase HRI-mediated stress response.

bioRxiv · Apr 14, 2022 · PreprintCell Biology

OMA1 mediates local and global stress responses against protein misfolding in CHCHD10 mitochondrial myopathy

M. K. Shammas, X. Huang, B. P. Wu, I. Song, N. Randolph, Y. Li, C. K. E. Bleck, D. Springer, C. Fratter, I. Barbosa, A. F. Powers, P. M. Quiros, C. Lopez-Otin, J. Poulton, D. P. Narendra

bioRxiv · Dec 21, 2021Cell Biology

Discovery of bactericides as an acute mitochondrial membrane damage inducer

R. Houston, Y. Sekine, M. B. Larsen, K. Murakami, D. P. Narendra, B. B. Chen, S. Sekine

The paper identifies Chlorhexidine and Alexidine as bactericides that induce acute mitochondrial membrane damage by altering inner mitochondrial membrane integrity and evoking a unique stress response.

bioRxiv · Apr 9, 2021Cell Biology

Loss of CHCHD2 and CHCHD10 activates OMA1 peptidase to disrupt mitochondrial cristae phenocopying patient mutations in vivo

Y.-T. Liu, X. Huang, D. Nguyen, E. Dombi, D. A. Springer, J. Poulton, S. Sekine, D. P. Narendra

This study shows that loss of CHCHD2 and CHCHD10 activates OMA1, leading to mitochondrial cristae disruption similar to patient mutations, linking C10 pathogenesis to C2/C10 function.

bioRxiv · Sep 18, 2019Cell Biology