Author

Y. Sekine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

R. Houston· 3 shared S. Sekine· 3 shared D. P. Narendra· 2 shared A. J. Nelson· 1 shared B. B. Chen· 1 shared D. A. Malide· 1 shared E. Fessler· 1 shared F. Seifuddin· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersCell Biology

R. Houston

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The contribution of Kaposis sarcoma-associated herpesvirus ORF7 and its zinc-finger motif to viral genome cleavage and capsid formation

Y. Iwaisako, T. Watanabe, Y. Sekine, Y. Suzuki, T. Nakano, M. Fujimuro

This study investigates the role of KSHV ORF7 and its zinc-finger motif in viral genome cleavage and capsid formation, revealing that ORF7 acts after ORF17 and is essential for proper capsid assembly and virion production.

bioRxiv · May 2, 2022Microbiology

A mitochondrial iron-sensing pathway regulated by DELE1

Y. Sekine, R. Houston, E. Fessler, L. T. Jae, D. P. Narendra, S. Sekine

This study identifies DELE1 as a mitochondrial protein whose import and stability are regulated by iron availability, linking mitochondrial function to the heme-regulated kinase HRI-mediated stress response.

bioRxiv · Apr 14, 2022 · PreprintCell Biology

Discovery of bactericides as an acute mitochondrial membrane damage inducer

R. Houston, Y. Sekine, M. B. Larsen, K. Murakami, D. P. Narendra, B. B. Chen, S. Sekine

The paper identifies Chlorhexidine and Alexidine as bactericides that induce acute mitochondrial membrane damage by altering inner mitochondrial membrane integrity and evoking a unique stress response.

bioRxiv · Apr 9, 2021Cell Biology

Acetylation-mediated phase control of the nucleolus regulates cellular acetyl-CoA responses

R. Houston, S. Sekine, M. J. Calderon, F. Seifuddin, G. Wang, H. Kawagishi, D. A. Malide, Y. Li, M. Gucek, M. Pirooznia, A. J. Nelson, M. P. Stokes, J. Stewart-Ornstein, S. G. Wendell, S. C. Watkins, , Y. Sekine

The paper shows that acetyl-CoA depletion disrupts nucleolar integrity, activates p53 via ribosomal proteins, and is mediated by class IIa HDACs regulating nucleolar phase state.

bioRxiv · Jan 24, 2020Cell Biology