Author

E. Gomez-Perdiguero

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

T. Weinberger· 2 shared A. Biton· 1 shared A. Hidalgo· 1 shared A. Todica· 1 shared C. Chen· 1 shared C. Garcia· 1 shared C. Kaiser· 1 shared C. Pridans· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

T. Weinberger

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Author profile →

4 papers

Recent·Most cited

Resident and recruited macrophages differentially contribute to cardiac healing after myocardial ischemia

T. Weinberger, D. Messerer, M. Joppich, M. Fischer, C. Garcia, K. Kumaraswami, V. Wimmler, S. Ablinger, S. Raeuber, J. Fang, L. Liu, W. H. Liu, J. Winterhalter, J. Lichti, L. Tomas, , C. Schulz

This study shows resident macrophages improve cardiac remodelling while recruited macrophages influence infarct size after myocardial ischemia/reperfusion injury.

bioRxiv · May 8, 2023Immunology

Inflammation drives age-induced loss of tissue resident macrophages

K. Ade, J. S. Coronilla, D. Obino, T. Weinberger, C. Kaiser, S. Mella, C. Chen, L. Katsimpardi, C. Werts, P. Dardenne, Y. Lallemand, E. Gomez-Perdiguero

The paper shows that inflammation causes age-related loss of tissue-resident macrophages, which cannot be replaced by hematopoietic stem cell-derived cells, and that reducing inflammation prevents this loss and improves liver aging.

bioRxiv · Oct 2, 2022 · PreprintImmunology

Overlapping Definitive Progenitor Waves Divide and Conquer to Build a Layered Hematopoietic System

L. Freyer, L. Iturri, A. Biton, E. Gomez-Perdiguero

This study shows that fetal yolk sac erythro-myeloid progenitors (EMP) are the main source of mature myeloid cells until birth, while hematopoietic stem cells (HSC) contribute little to fetal myelopoiesis.

bioRxiv · Dec 24, 2020 · PreprintImmunology

Functionally distinct resident macrophage subsets differentially shape responses to infection in the bladder

L. Lacerda Mariano, M. Rousseau, H. Varet, R. Legendre, R. Gentek, J. Saenz Coronilla, M. Bajenoff, E. Gomez-Perdiguero, M. A. Ingersoll

The paper identifies two distinct bladder macrophage subsets, shows their differential responses to infection, and demonstrates their impact on immune outcomes.

bioRxiv · Apr 18, 2020Immunology