Author

N. Herranz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

J. Gil· 2 shared A. Amadoz· 1 shared A. Celma· 1 shared A. Guerrero· 1 shared A. I. Choudhury· 1 shared A. Santamaria· 1 shared A. Sierra· 1 shared A. Uren· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersPhysiology

J. Gil

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A lncRNA-mediated metabolic rewiring of cell senescence

E. Grossi, F. P. Marchese, J. Gonzalez, E. Goni, J. M. Fernandez-Justel, A. Amadoz, N. Herranz, L. Puchades-Carrasco, M. Montes, M. Huarte

This study identifies sin-lncRNA, a long non-coding RNA that regulates mitochondrial metabolism during cellular senescence by modulating oxidative phosphorylation and DLST localization.

bioRxiv · Jan 25, 2024Cell Biology

Ribosomal S6 kinase 1 regulates inflammaging via the senescence secretome

S. Gallage, E. E. Irvine, S. Pedroni, J. E. Barragan Avila, S. Khadayate, J. Pombo, S. Brookes, D. Heide, G. Dharmalingam, A. I. Choudhury, N. Herranz, S. Vernia, M. Heikenwalder, J. Gil, D. J. Withers

This study shows that S6K1 deletion reduces inflammation and immune infiltration in aged livers, suggesting it suppresses the inflammatory SASP, contributing to healthspan benefits.

bioRxiv · Oct 17, 2023Physiology

Circulating tumor extracellular vesicles to monitor metastatic prostate cancer genomics and transcriptomic evolution

I. Casanova-Salas, S. Cordoba-Terreros, D. Aguilar, L. Agundez, J. Brandariz, N. Herranz, M. Gonzalez, R. Morales-Barrera, A. Sierra, M. Soriano-Navarro, P. Cresta, S. Simonetti, G. Rodrigues, S. Arce-Gallego, L. Delgado, , J. Mateo

This study shows that circulating tumor extracellular vesicles can be used to monitor genomic and transcriptomic changes in metastatic prostate cancer through liquid biopsy.

bioRxiv · Apr 14, 2023Cancer Biology

Galactose-modified duocarmycin prodrugs as senolytics

A. Guerrero, R. Guiho, N. Herranz, A. Uren, D. Withers, J. P. Martinez-Barbera, L. Tietze, J. Gil

This study develops galactose-modified duocarmycin prodrugs that selectively kill senescent cells by targeting lysosomal β-galactosidase, showing therapeutic potential for age-related diseases.

bioRxiv · Aug 24, 2019Cell Biology