Author

E. H. Klontz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

D. Deredge· 2 shared A. H. Aytenfisu· 1 shared A. MacKerell· 1 shared D. Liberg· 1 shared E. J. Sundberg· 1 shared E. Sundberg· 1 shared G. A. Snyder· 1 shared G. Forsberg· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

D. Deredge

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2 papers

Recent·Most cited

Molecular basis of selective cytokine signaling inhibition by antibodies targeting a shared receptor

J. K. Fields, K. Kihn, G. S. Birkedal, E. H. Klontz, K. Sjöström, S. Günther, R. Beadenkopf, G. Forsberg, D. Liberg, G. A. Snyder, D. Deredge, E. J. Sundberg

This study shows that antibodies targeting IL-1RAcP can selectively block signaling by different IL-1 family cytokines based on distinct epitopes they engage.

Frontiers in Immunology · Dec 24, 2021Peer-reviewedImmunology

Insights into substrate recognition and specificity for IgG by Endoglycosidase S2

A. H. Aytenfisu, D. Deredge, E. H. Klontz, J. Du, E. Sundberg, A. MacKerell

This study uses molecular dynamics simulations to model how EndoS2 interacts with IgG, revealing structural insights into its substrate recognition and catalytic mechanism.

bioRxiv · May 24, 2021Biophysics