Author
G. A. Snyder
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2021-2023 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 18 mutual co-author links4 papers
Recent·Most cited
The structure of NAD+ consuming protein Acinetobacter baumannii TIR domain shows unique kinetics and conformations.
E. Klontz, J. O. Obi, Y. Wang, G. Glendening, J. Carr, C. Tsibouris, S. Buddula, S. Nallar, A. Soares, D. Beckett, J. S. Redzic, E. Eisenmesser, C. Palm, K. Schmidt, A. Scudder, , G. A. Snyder
The paper reports the crystal structure of Acinetobacter baumannii TIR domain and its NAD+ hydrolase activity, showing conformational changes and kinetic effects upon substrate binding.
bioRxiv · May 19, 2023 · PreprintBiochemistry
CD36 homologs determine microbial resistance to the Lyme disease spirochete
A. J. O'Neal, N. Singh, I. S. Forrest, A. Rolandelli, X. Wang, D. K. Shaw, B. D. Young, S. Narasimhan, S. Dutta, G. A. Snyder, L. Marnin, L. R. Butler, S. Samaddar, M. T. Mendes, F. E. C. Paz, , J. H. F. Pedra
The paper identifies CD36 homologs as conserved lipid receptors mediating anti-Borrelia immunity in both ticks and humans.
bioRxiv · Feb 9, 2022 · PreprintImmunology
Molecular basis of selective cytokine signaling inhibition by antibodies targeting a shared receptor
J. K. Fields, K. Kihn, G. S. Birkedal, E. H. Klontz, K. Sjöström, S. Günther, R. Beadenkopf, G. Forsberg, D. Liberg, G. A. Snyder, D. Deredge, E. J. Sundberg
This study shows that antibodies targeting IL-1RAcP can selectively block signaling by different IL-1 family cytokines based on distinct epitopes they engage.
Frontiers in Immunology · Dec 24, 2021Peer-reviewedImmunology