Author

J. K. Fields

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Vaidya· 1 shared C. W. Hicks· 1 shared C. Wolberger· 1 shared D. Deredge· 1 shared D. Liberg· 1 shared E. H. Klontz· 1 shared E. J. Sundberg· 1 shared G. A. Snyder· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiophysics

A. Vaidya

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2 papers

Recent·Most cited

Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch

C. W. Hicks, S. Rahman, S. L. Gloor, J. K. Fields, N. L. Husby, A. Vaidya, K. E. Maier, M. Morgan, M.-C. Keogh, C. Wolberger

This study reveals that H2BK120ub blocks the nucleosome acidic patch, preventing protein binding, while H2AK119ub does not, highlighting distinct roles of these ubiquitinations in chromatin regulation.

bioRxiv · Feb 22, 2024Biophysics

Molecular basis of selective cytokine signaling inhibition by antibodies targeting a shared receptor

J. K. Fields, K. Kihn, G. S. Birkedal, E. H. Klontz, K. Sjöström, S. Günther, R. Beadenkopf, G. Forsberg, D. Liberg, G. A. Snyder, D. Deredge, E. J. Sundberg

This study shows that antibodies targeting IL-1RAcP can selectively block signaling by different IL-1 family cytokines based on distinct epitopes they engage.

bioRxiv · May 7, 2021Immunology