ImmunologyFrontiers in ImmunologyPeer-reviewed
Molecular basis of selective cytokine signaling inhibition by antibodies targeting a shared receptor
J. K. Fields, K. Kihn, G. S. Birkedal…·E. J. Sundberg
This study shows that antibodies targeting IL-1RAcP can selectively block signaling by different IL-1 family cytokines based on distinct epitopes they engage.
DOI 10.3389/fimmu.2021.779100