Control of the Endo-Lysosome Homeostasis by the Paracaspase MALT1 regulates Glioma Cell Survival
K. A. Jacobs, G. Andre-Gregoire, C. Maghe, Y. Li, A. Thys, E. Harford-Wright, K. Trillet, T. Douanne, J.-S. Frenel, N. Bidere, J. Gavard
This study shows that MALT1 regulates endo-lysosome homeostasis and glioma cell survival, with MALT1 inhibition leading to lysosomal-mediated cell death.
bioRxiv · Mar 23, 2019Cell Biology