Author

G. Andre-Gregoire

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

J. Gavard· 5 shared N. Bidere· 4 shared T. Douanne· 3 shared A. Thys· 2 shared C. Maghe· 2 shared J.-S. Frenel· 2 shared K. A. Jacobs· 2 shared K. Trillet· 2 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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5 shared papersCell Biology

J. Gavard

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

BCL-xL antagonizes the deleterious effects of KRAS on mitochondrial scaffolding

N. Belaid, A. Basseville, G. Andre-Gregoire, A. Fetiveau, L. Maillet, F. Guilloneau, M. Leduc, C. Guette, L. Desaubry, J. Gavard, F. Gautier, P. Juin

This study shows BCL-xL prevents KRAS from disrupting mitochondrial scaffolding by maintaining proximity to prohibitin 2 and preventing mitochondrial mass decrease.

bioRxiv · Apr 13, 2022 · PreprintCell Biology

The von Willebrand Factor stamps Plasmatic Extracellular Vesicles from Glioblastoma Patients

Q. Sabbagh, G. Andre-Gregoire, C. Alves-Nicolau, N. Bidere, E. Jouglar, L. Guevel, J.-S. Frenel, J. Gavard

The paper demonstrates that extracellular vesicles from glioblastoma patients can be reliably measured and show differential protein cargos, with von Willebrand Factor as a selective hallmark.

bioRxiv · Mar 25, 2021Cancer Biology

The Necroptosis Effector MLKL drives Small Extracellular Vesicle Release and Tumour Growth in Glioblastoma

G. Andre-Gregoire, T. Douanne, A. Thys, C. Maghe, K. A. Jacobs, C. Ballu, K. Trillet, I. Busnelli, V. Hyenne, J. G. GOETZ, N. Bidere, J. Gavard

This study identifies MLKL as a regulator of EV release from GSCs, showing its role in promoting tumour growth and suggesting EV targeting as a therapeutic strategy.

bioRxiv · Jan 12, 2021 · PreprintCell Biology

Control of the Endo-Lysosome Homeostasis by the Paracaspase MALT1 regulates Glioma Cell Survival

K. A. Jacobs, G. Andre-Gregoire, C. Maghe, Y. Li, A. Thys, E. Harford-Wright, K. Trillet, T. Douanne, J.-S. Frenel, N. Bidere, J. Gavard

This study shows that MALT1 regulates endo-lysosome homeostasis and glioma cell survival, with MALT1 inhibition leading to lysosomal-mediated cell death.

bioRxiv · Mar 23, 2019Cell Biology

Pannexin-1 Channels govern the Generation of Necroptotic small Extracellular Vesicles

T. Douanne, G. Andre-Gregoire, M. Feyeux, P. Hulin, J. Gavard, N. Bidere

The paper identifies MLKL-induced activation of PANX1 channels as a mechanism driving necroptosis-associated small extracellular vesicle generation.

bioRxiv · Feb 1, 2019Cell Biology