Endothelial cells elicit a pro-inflammatory response to SARS-COV-2 without productive viral infection
L. Schimmel, K. Y. Chew, C. Stocks, T. Yordanov, P. Essebier, A. Kulasinghe, J. Monkman, A. F. R. d. S. Miggiolaro, C. Cooper, L. De Noronha, A. K. Lagendijk, K. Schroder, L. Labzin, E. J. Gordon, K. R. Short
This study shows that endothelial cells can be infected by SARS-CoV-2 but do not produce infectious virus, instead triggering an inflammatory response through sensing adjacent infections.
bioRxiv · Feb 14, 2021 · PreprintCell Biology