Author

K. R. Short

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 3 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:human· 4 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

K. Y. Chew· 5 shared A. K. Lagendijk· 2 shared C. J. Stocks· 2 shared H. Bielefeldt-Ohmann· 2 shared K. Schroder· 2 shared T. Yordanov· 2 shared X. Wang· 2 shared A. A. Khromykh· 1 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

5 shared papersImmunology

K. Y. Chew

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Oxysterols drive inflammation via GPR183 during influenza virus and SARS-CoV-2 infection

C. X. Foo, S. Bartlett, K. Y. Chew, M. D. Ngo, H. Bielefeldt-Ohmann, B. J. Arachchige, B. Matthews, S. Reed, R. Wang, M. J. Sweet, L. Burr, J. E. Sinclair, R. Parry, A. Khromykh, K. R. Short, , K. Ronacher

This study identifies oxysterols and GPR183 as drivers of inflammation in the lung during influenza and SARS-CoV-2 infections, showing that targeting GPR183 reduces inflammation and disease severity.

bioRxiv · Jun 14, 2022Immunology

Macrophages only sense infectious SARS-CoV-2 when they express sufficient ACE2 to permit viral entry, where rapid cytokine responses then limit viral replication.

L. I. Labzin, K. Y. Chew, K. Eschke, X. Wang, T. Esposito, C. J. Stocks, J. Rae, R. Patrick, H. Mostafavi, B. Hill, T. Yordanov, C. L. Holley, S. Emming, S. Fritzlar, F. L. Mordant, , K. Schroder

The paper shows that ACE2-expressing macrophages allow SARS-CoV-2 entry and replication, triggering anti-viral responses, while ACE2-negative macrophages do not support viral entry or cytokine release.

bioRxiv · Mar 22, 2022 · PreprintImmunology

COVID-19 vaccine booster induces a strong CD8+ T cell response against Omicron variant epitopes in HLA-A*02:01+ individuals

A. T. Nguyen, C. Szeto, D. S. M. Chatzileontiadou, Z. W. M. Tong, M. J. Dewar-Oldis, L. Cooper, L. D. Murdolo, K. Y. Chew, K. E. Lineburg, A. Riboldi-Tunicliffe, R. Williamson, B. J. Gardiner, D. Jayasinghe, C. A. Lobos, Y. M. Ahn, , S. Gras

bioRxiv · Jan 12, 2022 · PreprintImmunology

Pediatric nasal epithelial cells are less permissive to SARS-CoV-2 replication compared to adult cells

Y. Zhu, K. Y. Chew, M. Wu, A. C. Karawita, G. McCallum, L. E. Steele, A. Yamamoto, L. L. Labzin, T. Yarlagadda, A. A. Khromykh, X. Wang, J. Sng, C. J. Stocks, Y. Xia, T. R. Kollmann, , K. R. Short

The paper compares SARS-CoV-2 replication in pediatric and adult nasal epithelial cells, finding lower viral titers in children for ancestral and Delta variants, but higher replication for Omicron.

bioRxiv · Mar 8, 2021 · PreprintMicrobiology

Endothelial cells elicit a pro-inflammatory response to SARS-COV-2 without productive viral infection

L. Schimmel, K. Y. Chew, C. Stocks, T. Yordanov, P. Essebier, A. Kulasinghe, J. Monkman, A. F. R. d. S. Miggiolaro, C. Cooper, L. De Noronha, A. K. Lagendijk, K. Schroder, L. Labzin, E. J. Gordon, K. R. Short

This study shows that endothelial cells can be infected by SARS-CoV-2 but do not produce infectious virus, instead triggering an inflammatory response through sensing adjacent infections.

bioRxiv · Feb 14, 2021 · PreprintCell Biology