Author

E. J. Rice

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

C. G. Danko· 4 shared A. C. Vill· 2 shared I. L. Brito· 2 shared A. Abuhashem· 1 shared A. G. Chivu· 1 shared A. Wikramanayake· 1 shared A.-K. Hadjantonakis· 1 shared B. A. Basso· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersCancer Biology

C. G. Danko

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4 papers

Recent·Most cited

Multi-omic study of genome-edited human colonoid models of colorectal cancer reveal genotype-specific patterns of microRNA regulation

J. W. Villanueva, F. C. Pan, E. J. Rice, Y.-H. Hung, M. Winnicki, S. Chen, C. G. Danko, P. Sethupathy

This study uses genome-edited human colonoids to identify genotype-specific miRNA regulation patterns in colorectal cancer, highlighting potential therapeutic targets.

bioRxiv · Jul 28, 2023 · PreprintCancer Biology

Evolution of promoter-proximal pausing enabled a new layer of transcription control

A. G. Chivu, B. A. Basso, A. Abuhashem, M. M. Leger, G. Barshad, E. J. Rice, A. C. Vill, W. Wong, S.-P. Chou, G. Chovatiya, R. Brady, J. Smith, A. Wikramanayake, C. Arenas-Mena, I. L. Brito, , C. G. Danko

The paper investigates the evolutionary emergence of RNA polymerase II pausing and its regulatory role across species.

bioRxiv · Feb 19, 2023Evolutionary Biology

Run-on sequencing reveals nascent transcriptomics of the human microbiome

A. C. Vill, C. G. Danko, E. J. Rice, I. De Vlaminck, I. L. Brito

This study applies PRO-seq to the human microbiome to profile nascent transcription, revealing taxon-specific RNAP pause motifs and concurrent transcription and cleavage of guide RNAs and tRNA fragments.

bioRxiv · Apr 22, 2022 · PreprintMicrobiology

ER-positive breast cancer cells are poised for RET-mediated endocrine resistance

S. Horibata, E. J. Rice, H. Zheng, L. J. Anguish, S. Coonrod, C. G. Danko

This study shows that ER+ breast cancer cells have the RET signaling pathway components but lack RET ligands needed for endocrine resistance, linking RET ligand expression to therapy response and survival.

bioRxiv · Sep 21, 2017Cancer Biology