E. J. Tsai

Extracellular Matrix Instability and Chronic Inflammation Underlie Maladaptive Right Ventricular Pressure Overload Remodeling and Failure in Male Mice

This study shows male mice with pulmonary artery banding develop severe right ventricular dysfunction and failure due to ECM instability and chronic inflammation, while females show more adaptive remodeling without these features.

Molecular Pathophysiology of Cardiac Injury and Cardiac Microthrombi in Fatal COVID-19: Insights from Clinico-histopathologic and Single Nuclei RNA Sequencing Analyses

This study identifies transcriptomic changes in cardiac fibroblasts associated with cardiac microthrombi in fatal COVID-19 through single nuclei RNA sequencing and clinical analyses.