Author

E. M. Goldys

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cell Biology· 2 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:human· 4 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:development & morphogenesis· 2 Assay:imaging· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. G. Anwer· 2 shared A. Habibalahi· 2 shared B. M. Thejer· 2 shared E. J. New· 2 shared H. Neubauer· 2 shared J. A. Jazayeri· 2 shared L. A. Weston· 2 shared M. A. Cahill· 2 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiophysics

A. G. Anwer

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Towards label-free non-invasive autofluorescence multispectral imaging for melanoma diagnosis

A. Knab, A. G. Anwer, B. Pedersen, S. Handley, A. G. Marupally, A. Habibalahi, E. M. Goldys

This study uses multispectral autofluorescence imaging to differentiate melanoma cells from fibroblasts and validates its potential for melanoma diagnosis.

bioRxiv · Sep 25, 2023Biophysics

Non-invasive, label-free optical analysis to detect aneuploidy within the inner cell mass of the preimplantation embryo

C. Y. Tan, S. B. Mahbub, C. A. Campugan, J. M. Campbell, A. Habibalahi, D. J. X. Chow, S. Mustafa, E. M. Goldys, K. R. Dunning

This study uses hyperspectral microscopy to distinguish euploid and aneuploid cells in mouse embryos by analyzing metabolic activity differences.

bioRxiv · Nov 1, 2020Cell Biology

Tissue engineered model of hepatic breast cancer micrometastasis shows host-dependent colonization patterns and drug responses

A. E. Guller, V. S. Rozova, I. Kuschnerus, Z. Khabir, A. Nadort, A. E. Garcia-Bennett, L. Liang, Y. Qian, E. M. Goldys, A. V. Zvyagin

This paper develops a 3D tissue engineered model of hepatic micrometastasis from triple negative breast cancer, showing host-dependent colonization patterns and drug responses.

bioRxiv · Jan 8, 2020Bioengineering

PGRMC1 phosphorylation and cell plasticity 2: genomic integrity and CpG methylation

B. M. Thejer, P. P. Adhikary, S. L. Teakel, J. Fang, P. A. Weston, S. Gurusinghe, A. G. Anwer, M. Gosnell, J. A. Jazayeri, M. Ludescher, L.-A. Gray, M. Pawlak, R. H. Wallace, S. D. Pant, M. Wong, , M. A. Cahill

This study shows that PGRMC1 phosphorylation mutants alter genomic stability, CpG methylation, and cell metabolism, suggesting a role in cellular plasticity and tissue differentiation.

bioRxiv · Sep 18, 2019Cell Biology

PGRMC1 phosphorylation and cell plasticity 1: glycolysis, mitochondria, tumor growth

B. M. Thejer, P. P. Adhikary, A. Kaur, S. L. Teakel, A. Van Oosterum, I. Seth, M. Pajic, K. M. Hannan, M. Pavy, P. Poh, J. A. Jazayeri, T. Zaw, D. Pascovici, M. Ludescher, M. Pawlak, , M. A. Cahill

This study shows that altering PGRMC1 phosphorylation in cancer cells affects energy metabolism, mitochondrial function, and tumor growth.

bioRxiv · Sep 6, 2019Cancer Biology

Spatial and temporal control of CRISPR/Cas9-mediated gene editing delivered via a light-triggered liposome system

Y. A. Aksoy, W. Chen, E. M. Goldys, W. Deng

This study develops a light-triggered liposome system for spatial and temporal control of CRISPR/Cas9 gene editing, achieving high knockout efficiency in both in vitro and in vivo models.

bioRxiv · Aug 5, 2019Bioengineering