Author

E. Rodriguez Araya

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

F. Calderon· 2 shared V. L. Alonso· 2 shared A. Pezza· 1 shared E. C. Serra· 1 shared E. Serra· 1 shared I. Pena· 1 shared I. Rioja· 1 shared J. Cantizani· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMicrobiology

F. Calderon

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Author profile →

2 papers

Recent·Most cited

Identification of novel Bromodomain inhibitors of Trypanosoma cruzi Bromodomain Factor 2 (TcBDF2) using a fluorescence polarization-base high-throughput assay

E. C. Serra, L. Tavernelli, V. L. Alonso, I. Pena, E. Rodriguez Araya, R. Manarin, J. Cantizani, J. Martin, J. Salamanca, P. Bamborough, F. Calderon, R. Gabarro

The paper develops a fluorescence polarization-based assay to identify bromodomain inhibitors of TcBDF2, finding 7 novel compounds that bind TcBDF2 with dissociation constants between 1 and 3 M.

bioRxiv · Feb 16, 2024 · PreprintMicrobiology

Essential bromodomain TcBDF2 as a drug target against Chagas disease

A. Pezza, L. E. Tavernelli, V. L. Alonso, V. G. Perdomo, R. C. Gabarro, R. Prinjha, E. Rodriguez Araya, I. Rioja, R. Docampo, F. Calderon, J. J. Martin, E. Serra

This paper identifies TcBDF2 as an essential bromodomain protein in Trypanosoma cruzi, showing its role in parasite survival and pathogenesis, and demonstrates its potential as a drug target.

bioRxiv · Jan 25, 2022Cell Biology