Author

R. Docampo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

A. D. Gitler· 1 shared A. Marian· 1 shared A. Pezza· 1 shared A. Sanyal· 1 shared B. S. Mantilla· 1 shared C. Cardoso· 1 shared C. Frankfater· 1 shared D. Fiedler· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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1 shared paperCell Biology

A. D. Gitler

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Essential bromodomain TcBDF2 as a drug target against Chagas disease

A. Pezza, L. E. Tavernelli, V. L. Alonso, V. G. Perdomo, R. C. Gabarro, R. Prinjha, E. Rodriguez Araya, I. Rioja, R. Docampo, F. Calderon, J. J. Martin, E. Serra

This paper identifies TcBDF2 as an essential bromodomain protein in Trypanosoma cruzi, showing its role in parasite survival and pathogenesis, and demonstrates its potential as a drug target.

bioRxiv · Jan 25, 2022Cell Biology

Poly(A)-binding protein is an ataxin-2 chaperone that emulsifies biomolecular condensates.

S. Boeynaems, Y. Dorone, A. Marian, V. Shabardina, G. Huang, G. Kim, A. Sanyal, N.-E. Sen, R. Docampo, I. Ruiz-Trillo, K. Lasker, G. Auburger, E. Kabashi, A. D. Gitler

The paper identifies a conserved 14aa sequence in ataxin-2 that acts as a condensation switch and reveals poly(A)-binding proteins as RNA-dependent chaperones that regulate this switch.

bioRxiv · Aug 23, 2021 · PreprintCell Biology

Lathosterol oxidase (sterol C5-desaturase) deletion confers resistance to amphotericin B and sensitivity to acidic stress in Leishmania major

Y. Ning, C. Frankfater, F.-F. Hsu, R. Soares, C. Cardoso, P. Nogueira, N. Lander, R. Docampo, K. Zhang

This study shows that deleting LSO in Leishmania major confers amphotericin B resistance but causes sensitivity to acidic stress and membrane disruption.

bioRxiv · Apr 20, 2020Microbiology

Protein Targets of Inositol Pyrophosphate (5-IP7) in the parasite Trypanosoma cruzi

B. S. Mantilla, N. Brown, D. Fiedler, R. Docampo

This study identifies 5-IP7 protein targets in Trypanosoma cruzi using affinity pull-down and mass spectrometry, revealing distinct target profiles in different proliferative stages and potential therapeutic targets.

bioRxiv · Jan 9, 2020 · PreprintMicrobiology