Author

E. S. Egorov

Pirogov Russian National Research Medical University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Assay:scRNA-seq· 3 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Franke· 2 shared D. M. Chudakov· 2 shared A. A. Minervina· 1 shared A. Altunina· 1 shared A. L. Sycheva· 1 shared A. Walczak· 1 shared A. Y. Komkov· 1 shared Andreas BosioiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersImmunology

A. Franke

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Author profile →

3 papers

Recent·Most cited

Discovery of rare antigen-specific TCRs via replicate profiling

E. S. Egorov, Valeriia Kriukova, И. А. Шагина, G. V. Sharonov, K. Lupyr, Dmitriy B. Staroverov, Daniil K. Lukyanov, Maria A. Salnikova, R. V. Nikolaev, L. Shelikhova, Gayane A Lopukhova, A. Altunina, Ilnar Muftakhutdinov, Maria A Turchaniniova, OV Britanova, , Е. О. Серебровская

The paper develops a high-throughput TCR discovery assay to identify antigen-specific T cells, finding over 90 SARS-CoV-2-specific TCR clonotypes in one donor and nearly 1,000 in five donors.

Scientific Reports · Sep 24, 2026Peer-reviewedImmunology

Splicing-aware resolution of scRNA-Seq data

D. K. Lukyanov, E. S. Egorov, V. V. Kriukova, K. Ladell, D. Price, A. Franke, D. M. Chudakov

The paper introduces SANSARA, a method for splicing-aware scRNA-Seq analysis, revealing splicing heterogeneity in T cell subsets and interactions between transcription factors.

bioRxiv · Mar 25, 2024 · PreprintImmunology

Precise tracking of vaccine-responding T-cell clones reveals convergent and personalized response in identical twins

M. V. Pogorelyy, A. A. Minervina, M. Puelma Touzel, A. L. Sycheva, E. A. Komech, E. I. Kovalenko, G. G. Karganova, E. S. Egorov, A. Y. Komkov, D. M. Chudakov, I. Z. Mamedov, T. Mora, A. Walczak, Y. B. Lebedev

The paper develops a statistical framework to detect TCR clone changes in vaccinated twins and finds convergent yet personalized TCR responses.

bioRxiv · Apr 13, 2018Immunology