DNA methylation across the genome in aged human skeletal muscle tissue and stem cells: The role of HOX genes and physical activity
D. C. Turner, P. P. Gorski, M. F. Maasar, R. A. Seaborne, P. Baumert, A. D. Brown, M. O. Kitchen, R. M. Erskine, I. Dos-Remedios, S. Voisin, N. Eynon, R. I. Sultanov, O. V. Borisov, A. K. Larin, E. A. Semenova, , A. P. Sharples
This study identifies age-related hypermethylation in HOX genes in aged human skeletal muscle and stem cells, with physical activity inversely affecting methylation in some genes.
bioRxiv · Dec 27, 2019Physiology