Author

P. P. Gorski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Physiology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:chromatin & epigenetic regulation· 3 Assay:DNA methylation· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

A. P. Sharples· 4 shared D. C. Turner· 4 shared R. A. Seaborne· 3 shared B. Drust· 2 shared C. E. Stewart· 2 shared D. J. Owens· 2 shared M. F. Maasar· 2 shared A. D. Brown· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersPhysiology

A. P. Sharples

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Human skeletal muscle methylome after low carbohydrate energy balanced exercise

P. P. Gorski, D. C. Turner, J. Iraki, J. P. Morton, A. P. Sharples, J. L. Areta

This study examines DNA methylation changes in human skeletal muscle after low carbohydrate exercise under energy balance and deficit conditions, identifying hypomethylation in gene regions linked to metabolic pathways.

bioRxiv · Jan 19, 2023Physiology

The methylome and comparative transcriptome after high intensity sprint exercise in human skeletal muscle

M. F. Maasar, D. C. Turner, P. P. Gorski, R. A. Seaborne, J. A. Strauss, S. O. Shepherd, M. Cocks, N. J. Pillon, J. R. Zierath, A. T. Hulton, B. Drust, A. P. Sharples

This study examines the methylome and transcriptome changes in human skeletal muscle after high-intensity sprint exercise, finding that change of direction exercise causes greater epigenetic and gene expression changes than straight line sprinting.

bioRxiv · Sep 11, 2020 · PreprintPhysiology

Knockdown of the E3 Ubiquitin ligase UBR5 and its role in skeletal muscle anabolism

D. C. Turner, D. C. Hughes, L. M. Baehr, R. A. Seaborne, M. Viggars, J. C. Jarvis, P. P. Gorski, C. E. Stewart, D. J. Owens, S. C. Bodine, A. P. Sharples

This study shows that knocking down UBR5 leads to skeletal muscle atrophy by disrupting anabolic signaling pathways.

bioRxiv · Jun 5, 2020Cell Biology

DNA methylation across the genome in aged human skeletal muscle tissue and stem cells: The role of HOX genes and physical activity

D. C. Turner, P. P. Gorski, M. F. Maasar, R. A. Seaborne, P. Baumert, A. D. Brown, M. O. Kitchen, R. M. Erskine, I. Dos-Remedios, S. Voisin, N. Eynon, R. I. Sultanov, O. V. Borisov, A. K. Larin, E. A. Semenova, , A. P. Sharples

This study identifies age-related hypermethylation in HOX genes in aged human skeletal muscle and stem cells, with physical activity inversely affecting methylation in some genes.

bioRxiv · Dec 27, 2019Physiology