Tripartite interactions between filamentous Pf4 bacteriophage, Pseudomonas aeruginosa, and bacterivorous nematodes
C. M. Schwartzkopf, A. J. Robinson, M. Ellenbecker, D. R. Faith, D. M. Brooks, L. Lewerke, E. Voronina, A. A. Dandekar, P. R. Secor
This study shows that curing Pseudomonas aeruginosa of Pf4 phage infection increases virulence in C. elegans by enhancing PQS quorum sensing and pyocyanin production, but nematodes unable to detect bacterial pigments are more susceptible to the Pf4-cured strain.
bioRxiv · Oct 11, 2022Microbiology