Author

C. M. Schwartzkopf

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:bacteria (other)· 3 Research Focus:cell type annotation· 2 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

P. R. Secor· 4 shared D. R. Faith· 3 shared A. J. Robinson· 2 shared A. Joyce· 2 shared A. K. Schmidt· 2 shared D. M. Brooks· 2 shared A. A. Dandekar· 1 shared A. Coluccio· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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4 shared papersMicrobiology

P. R. Secor

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4 papers

Recent·Most cited

Targeted deletion of Pf prophages from diverse Pseudomonas aeruginosa isolates impacts quorum sensing and virulence traits

A. K. Schmidt, C. M. Schwartzkopf, J. D. Pourtois, E. Burgener, D. R. Faith, A. Joyce, T. Lamma, G. Kumar, P. L. Bollyky, P. R. Secor

This study deletes Pf prophages from P. aeruginosa isolates and examines their impact on quorum sensing, biofilm formation, and virulence traits.

bioRxiv · Nov 19, 2023 · PreprintMicrobiology

Inhibition of PQS signaling by the Pf bacteriophage protein PfsE enhances viral replication in Pseudomonas aeruginosa

C. M. Schwartzkopf, V. L. Taylor, M.-C. Groleau, D. R. Faith, A. K. Schmidt, T. L. Lamma, D. M. Brooks, E. Deziel, K. L. Maxwell, P. R. Secor

The paper identifies PfsE as a Pf phage protein that inhibits PQS quorum sensing and type IV pili extension, enhancing viral replication and protecting the host from competing phages.

bioRxiv · Aug 25, 2023Microbiology

Tripartite interactions between filamentous Pf4 bacteriophage, Pseudomonas aeruginosa, and bacterivorous nematodes

C. M. Schwartzkopf, A. J. Robinson, M. Ellenbecker, D. R. Faith, D. M. Brooks, L. Lewerke, E. Voronina, A. A. Dandekar, P. R. Secor

This study shows that curing Pseudomonas aeruginosa of Pf4 phage infection increases virulence in C. elegans by enhancing PQS quorum sensing and pyocyanin production, but nematodes unable to detect bacterial pigments are more susceptible to the Pf4-cured strain.

bioRxiv · Oct 11, 2022Microbiology

Bacterial threat assessment of bacteriophage infection is mediated by intracellular polyamine accumulation and Gac/Rsm signaling

C. D. de Mattos, A. Nemudryi, D. Faith, D. C. Bublitz, L. Hammond, M. Kinnersley, C. M. Schwartzkopf, A. J. Robinson, A. Joyce, L. A. Michaels, R. Brzozowski, A. Coluccio, D. Xing, J. Uchiyama, L. K. Jennings, , P. R. Secor

This study shows that Pseudomonas aeruginosa uses intracellular polyamine accumulation and Gac/Rsm signaling to assess bacterial cell death and inhibit phage replication.

bioRxiv · Apr 1, 2022Microbiology