THEMIS is a priming substrate of non-receptor tyrosine phosphatase PTPN6/SHP1 and plays dual roles during T cell development
J. Zhang, E. Zuo, M. Song, L. Chen, Z. Jiang, S. Chen, X. Xiong, Y. Wang, P. Hao, T. Horng, M. Zhuang, L. Zhang, H. Wang, G. Fan
This study identifies THEMIS as a substrate of SHP1 and shows it has phosphorylation-dependent and -independent roles in T cell development.
bioRxiv · Dec 21, 2021 · PreprintCell Biology