Author

Edward Morrissey

AstraZeneca (United Kingdom)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:graph neural network· 1

Frequent Co-Authors

Anna M Nicholson· 1 shared Avid M. AfzaliD· 1 shared Cecilia Lindskog· 1 shared Cerys Tatton· 1 shared Cora Olpe· 1 shared Doran Khamis· 1 shared Douglas J Winton· 1 shared Evangelia PetsalakiiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Anna M Nicholson

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2 papers

Recent·Most cited

Biological Network Organization, Not Generic Graph Topology, Drives Graph-Based Gene Essentiality Prediction

Setareh Rahimi, S M Bonner, Avid M. Afzal, Marta Milo, Edward Morrissey, Evangelia Petsalaki

This study evaluates whether graph-based gene essentiality prediction relies on biological network structure or generic graph topology, finding that biological connectivity is critical for performance.

bioRxiv · Jul 4, 2026 · PreprintSystems Biology

A diffusion-like process enables expansion of advantaged gene mutations in human colonic epithelium

Cora Olpe, Doran Khamis, Maria Chukanova, Richard Kemp, Kate Marks, Cerys Tatton, Cecilia Lindskog, Nefeli Skoufou-Papoutsaki, Anna M Nicholson, Roxanne Brunton-Sim, Shalini Malhotra, Rogier ten Hoopen, Rachel Stanley, Edward Morrissey, Douglas J Winton

The paper quantifies clonal expansion of KDM6A-negative mutations in human colonic epithelium and proposes crypt diffusion as a mechanism for accommodating clonal growth.

bioRxiv · Jul 10, 2020 · PreprintCancer Biology