Author

Maria Chukanova

University of Cambridge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:imaging· 1 Approach:statistical model· 1

Frequent Co-Authors

Anna M Nicholson· 1 shared Anna Maria Siegert· 1 shared Brian LamiD· 1 shared Cecilia Lindskog· 1 shared Cerys Tatton· 1 shared Cora Olpe· 1 shared Danish SaleheeniD· 1 shared Dirk S. PauliD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Anna M Nicholson

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2 papers

Recent·Most cited

Protein-truncating variants in BSN are associated with severe adult-onset obesity, type 2 diabetes and fatty liver disease

Yajie Zhao, Maria Chukanova, Katherine A. Kentistou, Zammy Fairhurst-Hunter, Anna Maria Siegert, Raina Jia, Georgina K.C. Dowsett, Eugene J. Gardner, Felix R. Day, Lena R Kaisinger, Yi‐Chun Loraine Tung, Brian Lam, Hsiao‐Jou Cortina Chen, Quanli Wang, Jaime Berumen-Campos, , John R. B. Perry

The paper identifies protein-truncating variants in BSN associated with severe adult-onset obesity, type 2 diabetes, and fatty liver disease, with no effect on childhood adiposity.

medRxiv · Jun 14, 2023 · PreprintGenetic & Genomic Medicine

A diffusion-like process enables expansion of advantaged gene mutations in human colonic epithelium

Cora Olpe, Doran Khamis, Maria Chukanova, Richard Kemp, Kate Marks, Cerys Tatton, Cecilia Lindskog, Nefeli Skoufou-Papoutsaki, Anna M Nicholson, Roxanne Brunton-Sim, Shalini Malhotra, Rogier ten Hoopen, Rachel Stanley, Edward Morrissey, Douglas J Winton

The paper quantifies clonal expansion of KDM6A-negative mutations in human colonic epithelium and proposes crypt diffusion as a mechanism for accommodating clonal growth.

bioRxiv · Jul 10, 2020 · PreprintCancer Biology