Nonlinear progression during the occult transition establishes cancer lethality
Joshua D. Ginzel, Henry Chapman, Joelle E. Sills, Edwin J. Allen, Larry S. Barak, Robert D. Cardiff, Alexander D. Borowsky, Herbert Kim Lyerly, Bruce W. Rogers, Joshua C. Snyder
This study shows that cancer progression is nonlinear, with a critical occult transition leading to lethal tumors before detection, challenging the linear model of cancer growth.
Disease Models & Mechanisms · Mar 1, 2025Peer-reviewedCancer Biology