Recording proteome dynamics in the late-stage embryo at hour-timescale, spatial, and single-cell resolution with MEMBRYO
Marta Couce-Iglesias, Eleonora Oliani, Robert Kerridge, Florian Mutschler, Daniela Sofia Valdes, Anna Sophie Welter, Beata Lukaszewska‐McGreal, David Meierhofer, Koshi Imami, Eugenio F. Fornasiero, Fabian Coscia, Matthias Selbach, Matthew L. Kraushar
The paper introduces MEMBRYO, a method for continuous SILAC proteomics in live embryos, revealing post-transcriptional regulation during neurogenesis.
bioRxiv · Sep 28, 2026 · PreprintDevelopmental Biology