Author

Florian Mutschler

German Cancer Research CenterORCID 0009-0002-0992-7171Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Anna Sophie WelteriD· 2 shared Matthias SelbachiD· 2 shared Robert Kerridge· 2 shared Ann-Christin Branscheid· 1 shared Artür ManukyaniD· 1 shared Beata Lukaszewska‐McGreal· 1 shared Chiara GiacomelliiD· 1 shared Daniela Sofia ValdesiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersDevelopmental Biology

Anna Sophie WelterORCID

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2 papers

Recent·Most cited

Recording proteome dynamics in the late-stage embryo at hour-timescale, spatial, and single-cell resolution with MEMBRYO

Marta Couce-Iglesias, Eleonora Oliani, Robert Kerridge, Florian Mutschler, Daniela Sofia Valdes, Anna Sophie Welter, Beata Lukaszewska‐McGreal, David Meierhofer, Koshi Imami, Eugenio F. Fornasiero, Fabian Coscia, Matthias Selbach, Matthew L. Kraushar

The paper introduces MEMBRYO, a method for continuous SILAC proteomics in live embryos, revealing post-transcriptional regulation during neurogenesis.

bioRxiv · Sep 28, 2026 · PreprintDevelopmental Biology

Global quantification of mammalian gene expression noise

Anna Sophie Welter, Florian Mutschler, M. Celeste Simon, Chiara Giacomelli, Ann-Christin Branscheid, Artür Manukyan, Luiz Gustavo Teixeira Alves, Maximilian Gerwien, Robert Kerridge, Markus Landthaler, Jana Wolf, Matthias Selbach

The paper quantifies gene expression noise in mammalian cells using single-cell proteomics and finds that noise is largely extrinsic and structured across cellular states.

bioRxiv · May 14, 2026 · PreprintSystems Biology