A new bioorthogonal PET reporter gene for cardiac regenerative medicine binding to DTPA-lanthanide complexes
Sepideh Seyfi, Tatjana Dorn, Christine M Poch, Martin Grashei, Eleonore Baier, Volker Morath, Veronika Fricke, Katja Fritschle, Arne Skerra, Markus Schwaiger, Christian Kupatt, Karl-Ludwig Laugwitz, Alessandra Moretti, Wolfgang Weber
This paper develops a bioorthogonal PET reporter gene for tracking hiPSC-derived cardiac cells in vitro and ex vivo, showing it maintains function without adverse effects.
bioRxiv · Sep 28, 2026 · PreprintBioengineering