Keisuke Nagao

Adrenal remodeling encodes stress axis memory to shape fentanyl seeking

This study shows that fentanyl interacts with the HPA axis over different timescales, with adrenal remodeling encoding stress history to influence fentanyl-seeking behavior.

Targeted Magnetic Nanodiscs for Wireless Causal Manipulation of Gut-Brain Circuits

This paper develops magnetic nanodiscs for wireless, cell-type specific activation of gut-brain circuits, showing they can regulate feeding behavior through hindbrain satiety circuits.

CHARIOT-AAV: Conjugation of diverse vectors to adeno-associated viruses for delivery of large genes

CHARIOT-AAV conjugates diverse vectors to AAVs to enable tissue-specific delivery and expanded cargo capacity for large genes.

Adeno-associated viruses escort nanomaterials to specific cells and tissues

This paper demonstrates that adeno-associated viruses can be coupled to nanoparticles to deliver them specifically to target tissues, with an example of brain-targeting using AAV serotype CAP-B10.

Fiber-based Probes for Electrophysiology, Photometry, Optical and Electrical Stimulation, Drug Delivery, and Fast-Scan Cyclic Voltammetry In Vivo

This paper introduces multifunctional fiber-based probes capable of recording and modulating neuronal activity, chemical signaling, and delivering drugs in vivo, demonstrating their utility in studying brain function.