Polina Anikeeva

This study shows that fentanyl interacts with the HPA axis over different timescales, with adrenal remodeling encoding stress history to influence fentanyl-seeking behavior.

This study models prodromal Parkinson's disease in mice by exposing them to rotenone, revealing GI dysfunction and early brain pathology without significant motor deficits.

This study shows that optogenetic stimulation of cholinergic vagal neurons reduces pro-inflammatory cytokines, while glutamatergic stimulation does not, demonstrating the importance of pathway selectivity in vagus nerve stimulation.

This paper develops magnetic nanodiscs for wireless, cell-type specific activation of gut-brain circuits, showing they can regulate feeding behavior through hindbrain satiety circuits.

CHARIOT-AAV conjugates diverse vectors to AAVs to enable tissue-specific delivery and expanded cargo capacity for large genes.

This paper introduces a multilayered nanomembrane platform for stretchable metal electronics, achieving high conductivity at extreme strains through crack-bridging pathways.

This study develops magnetoelectric nanodiscs (MENDs) for deep brain stimulation in Parkinson's disease models, showing motor improvements and reduced oxidative stress compared to traditional DBS.

This paper demonstrates that adeno-associated viruses can be coupled to nanoparticles to deliver them specifically to target tissues, with an example of brain-targeting using AAV serotype CAP-B10.

This paper introduces multifunctional fiber-based probes capable of recording and modulating neuronal activity, chemical signaling, and delivering drugs in vivo, demonstrating their utility in studying brain function.

The paper demonstrates the use of multifunctional fibers to record and modulate neural activity in macaques during cognitive tasks, showing changes in neural activity with local inhibition.

The paper shows that neuropod cells in the gut detect caloric sugars via SGLT1 or sweet taste receptors, guiding sugar preference by signaling the brain through glutamate release.

This paper develops new fabrication methods for multifunctional neural interfaces that integrate electrical, optical, and microfluidic functions, demonstrating their long-term viability in mice.

This paper develops multifunctional fibers to deliver light and photoswitchable ligands to deep brain regions in mice, enabling optogenetic control of behavior through TRPV1 activation.