Pantelis Hatzis

This paper shows HBx promotes hepatocyte survival and reduces differentiation in human liver organoids, potentially contributing to liver cancer.

The paper examines how transitioning to agroforestry in a Mediterranean orchard affects insect diversity and soil function over a 10-year period.

This study identifies Trithorax as a key factor maintaining ISC lineage fidelity by repressing EE specification through Ptx1-mediated mechanisms in Drosophila midgut.

This paper introduces EL244, a dual ATX inhibitor and PPARγ agonist for treating pulmonary fibrosis, showing reduced LPA levels and fibrosis in a bleomycin model.

This study shows iNKT cells both promote and inhibit hepatocellular carcinoma (HCC) development, with their role shifting from early promotion to later tumor control.

This study examines how short-term animal product restriction alters the human gut microbiome and host plasma biology in a religiously motivated dietary group.

The paper identifies CHEK1 and BIRC5 as therapeutic targets in ARID1A-deficient bladder cancer using patient-derived tumoroids and public datasets.

This study identifies TKS5-mediated podosome formation in IPF fibroblasts as a driver of ECM invasion and pulmonary fibrosis, with potential therapeutic targeting via src kinase inhibition.

Catchet-MS identifies thalidomide analogues targeting IKZF1 as novel HIV-1 latency reversal agents by reversing latency in CD4+ T-cells.

This study identifies 10 novel host factors involved in HIV latency using a haploid genetic screen and validates their roles through functional assays and drug testing.