BiochemistrybioRxivPreprint
Rational design of tertiary coordination sphere of a heme-based sensor for two-orders enhanced oxygen affinity
Anoop Rama Damodaran, Eaindra Yee, Rahul L. Khade…·Ambika Bhagi‐Damodaran
This study enhances the oxygen affinity of the DosS protein by modifying its heme coordination sphere, achieving a 150-fold increase in O2 binding affinity.
DOI 10.1101/2025.05.27.656425